Faculty Candidate Talk
See POT 7th floor bulletin board for details.
See POT 7th floor bulletin board for details.
See POT 7th floor bulletin board for details
See POT 7th floor bulleting board for details
See POT 7th floor bulletin board for details.
See POT 7th floor bulletin board for details.
Please see POT 7th floor bulletin board for details.
Please see POT 7th floor bulletin board for details
Title: Topics in Mathematical Cell Biology: Cell polarity, embryogenesis, and central nervous system regeneration
Abstract: I will give an overview of my work in mathematical cell biology. First I will discuss topics related to polarity, specifically in the context of cell movement. This and numerous other cell functions require identification a “front” and “back” (e.g. polarity). In some cases this can form spontaneously and in others sufficiently large stimuli are required. I will discuss a mechanistic theory for how cells might transition between these behaviors by modulating their sensitivity to external stimuli. In order to address this and analyze the models being presented, I will describe a new bifurcation technique, the Local Perturbation Analysis, for analyzing complex, spatial biochemical networks.
Additionally, I will discuss work related to early development of the mammalian embryo. A vital first step in this process is the formation of an early placenta prior to implantation. I will discuss a stochastic model of this spatial patterning event and show that systemic noise, rather than being a hindrance, is vital to the functioning of this process. Time permitting I will also describe modeling of central nervous system regeneration after injury or disease. In particular, I will discuss how individual cell behaviors can be controlled (either naturally or through therapeutic means) to optimize the regeneration response.
A reception will be held at 3:30 p.m. in POT 745.