The Jun/miR-22/HuR regulatory axis contributes to tumourigenesis in colorectal cancer.
| Author | |
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| Abstract | :
Colorectal cancer (CRC) is a severe health problem worldwide. Clarifying the mechanisms for the deregulation of oncogenes and tumour suppressors in CRC is vital for its diagnosis, treatment, prognosis and prevention. Hu antigen R (HuR), which is highly upregulated in CRC, functions as a pivotal oncogene to promote CRC progression. However, the underlying cause of its dysregulation is poorly understood. |
| Year of Publication | :
2018
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| Journal | :
Molecular cancer
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| Volume | :
17
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| Issue | :
1
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| Number of Pages | :
11
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| Date Published | :
2018
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| URL | :
https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-017-0751-3
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| DOI | :
10.1186/s12943-017-0751-3
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| Short Title | :
Mol Cancer
|
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